Comparison of two medications for producing memory loss during General Anesthesia

Comparison the extent of amnesia produced by Dexmedetomidine and Midazolam as pre-medication during General Anesthesia: A Randomized Double Blinded Controlled Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/09/094116

Enrollment

Registered

2025-09-02

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Premedication with Inj Dexmedetomidine: Premedication with Inj Dexmedetomidine- 0.05mg/kg IV over 50 seconds Control Intervention1: Premedication with Inj Midazolam: Premedication with

Eligibility

Inclusion criteria

Inclusion criteria: 1 Adult participants of 18 to 60 years 2 Elective cases posted for surgery under general anaesthesia 3 Participants with American Society of Anaesthesiologist physical status I and II 4 Surgeries lasting less than 2 hours

Exclusion criteria

Exclusion criteria: 1 Participants who do not consent 2 Pregnant participants 3 Participants who have any diagnosed psychiatric disorder or addictions 4 Participants receiving ketamine 5 Participants with a history of allergy to Midazolam or Dexmedetomidine

Design outcomes

Primary

Measure	Time frame
Inability to recall the Images displayed to the patient pre-operativelyTimepoint: Preoperatively and 15 minutes after extubation	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Ketakee Ganu

Tomo Riba Institute Of Health And Medical Sciences

drnaomisaring@gmail.com9422722898

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026