Comparison Between magnesium sulphate and ketamine as analgesia in adult patients for laparoscopic cholecystectomy in a tertiary care center double blind randomized controlled study

A comparative study Between magnesium sulphate and ketamine as analgesic in adult patients for laparoscopic cholecystectomy in a tertiary care center double blind randomized controlled study - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094105

Enrollment

Registered

2025-09-02

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Magnesium sulphate: 1gm as iv bolus over 5min before intubation and 0.5 gm/hr as in infusion during surgery Control Intervention1: Ketamine: 0.5mg/kg iv bolus for 5 minutes before intub

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 BMI 18-28 kg/m2 all patients posted for laparoscopic cholecyestectomy

Exclusion criteria

Exclusion criteria: on sedatives/hypnoticspreoperatively psychiatric illness/alcohol abuse patient with known history to allergy to study drug pregnant and lactating mothers surgery duration more than 3 hours

Design outcomes

Primary

Measure	Time frame
to compare the analgesic effects of intravenous magnesium sulphate and inravenous ketamine in adult patients for laparoscopic cholecystectomy by NRS scoring postoperativelyTimepoint: To access pain by NRS scoring system postoperatively for first 24 hours	—

Secondary

Measure	Time frame
to compare the hemodynamic responsesintraoperatively with intravenous magnesium sulphate and inravenous ketamineTimepoint: intraoperatively hemodynamic response with study drug and surgery procedure less than 3 hours	—

Countries

India

Contacts

Public ContactDr prashanth prabhu j

sapthagiri institue of medical sciences bengaluru

prashanthjnpl@gmail.com9035067161

Outcome results