Effect of steroid in care of children admitted with Acute respiratory distress syndrome in reducing hospital stay

Effect of Methylprednisolone in Paediatric Acute Respiratory Distress Syndrome in addition to standard care on length of hospital stay - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/094073

Enrollment

Registered

2025-09-01

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J80- Acute respiratory distress syndrome

Interventions

Intervention1: Methylprednisolone infusion: Methylprednisolone will be used as an intervention medication. Dose of Methylprednisolone will be reconstituted in 50ml Normal saline with a final strength

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age group: 1month -18years 2. Diagnosis of ARDS based on PALICC 2 consensus guidelines 3. Mechanically ventilated for less than 72 hrs.

Exclusion criteria

Exclusion criteria: 1. Patients receiving steroids already 2. Terminally ill or on hospise care 3. Immunosuppressed 4. Extensive burns 5. Adrenal insufficiency 6. Invasive fungal infection 7. Chronic liver disease 8. Gastrointestinal bleed in past 1 month

Design outcomes

Primary

Measure	Time frame
Length of hospital stayTimepoint: date of discharge from hospital-date of randomisation	—

Secondary

Measure	Time frame
Ventilator free days 2. Length of PICU stay 3. 28 day?s mortalityTimepoint: 28 days ? date of extubation	—

Countries

India

Contacts

Public ContactDr Varsha

ABVIMS and Dr RML hospital, delhi

sudhach83@rediffmail.com7982425172

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026