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Comparision of two different doses of morphine given by epidural catheter for pain relief after normal vaginal delivery.

A Comparative Evaluation Analgesic Efficacy and Side Effect Profile of 1 mg vs 2 mg Epidural Morphine for Post-Vaginal Delivery Analgesia: A Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/094029
Enrollment
114
Registered
2025-09-01
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O759- Complication of labor and delivery, unspecified

Interventions

Intervention1: 1 mg morphine: 1 mg morphine in 6 mL saline via epidural catheter Single dose will be given prior to removal of epidural catheter Control Intervention1: 2 mg morphine: 2 mg morphine in

Sponsors

Dept of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women aged 19 45 years Singleton term pregnancy (more than or equal to 37 weeks) Vaginal delivery with labour epidural analgesia Able to provide informed consent

Exclusion criteria

Exclusion criteria: Known allergy to morphine or opioids History of chronic pain or opioid use Severe obstetric complications (eg PPH requiring transfusion) Emergency caesarean section delivery Denied consent for postpartum epidural morphine

Design outcomes

Primary

MeasureTime frame
Requirement of rescue analgesia within 24 hours of epidural morphine administrationTimepoint: Requirement of rescue analgesia within 24 hours of epidural morphine administration—

Secondary

MeasureTime frame
Incidence and severity of side effectsTimepoint: within 24 hours;Time to first rescue analgesiaTimepoint: within 24 hours;VAS pain scoresTimepoint: 6 and 12 and 24 hours post epidural morphine administration;Patient satisfaction score (0 10 scale)Timepoint: AT 24 hours—

Countries

India

Contacts

Public ContactANISH KRISHNA G

Dept of Anaesthesiology and Critical Care, AFMC, Pune

araymohapatra@gmail.com7276632896

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026