Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intraperitoneal instillation of Bupivacaine 0.25% (35 mL) with Dexmedetomidine 0.5 mcg/kg: Route: Intraperitoneal
Timing: At the end of surgery, before trocar removal
Frequency: Singl
Sponsors
Dr Prakriti Choudhury
Eligibility
Inclusion criteria
Inclusion criteria: ASA grade I or II Age between 18 and 65 years Hemodynamically stable Undergoing elective laparoscopic cholecystectomy Provided written informed consent
Exclusion criteria
Exclusion criteria: Emergency procedures Significant comorbidities (neurological, cardiac, respiratory, metabolic, hepatic, renal) Coagulation disorders Known allergy to study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time duration (in hours) from the completion of surgery to the time patient requested for first rescue analgesic medication.Timepoint: From the end of surgery (trocar removal) until the first patient request for rescue analgesia, within the first 24 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 .The total rescue analgesic dose requirements in first 24 hours post operatively. 2. The intensity of pain using Visual Analog Scale (VAS) score Immediately postoperatively Hourly up to first 4 hours(1,2,3,4 hrs) Every 4 hours upto 12 hours(8,12 hrs) At 24 hours 3.Heart Rate(bpm) & MAP(mmHg) (Observation time same as vas)Timepoint: Immediately postoperatively Hourly up to first 4 hours(1,2,3,4 hrs) Every 4 hours upto 12 hours(8,12 hrs) At 24 hours | — |
Countries
India
Contacts
Public ContactDr Prakriti Choudhury
Pradyumna Bal Memorial Hospital, Kalinga Institute of Medical Sciences
Outcome results
None listed