Health Condition 1: M259- Joint disorder, unspecified Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Injectable platelet rich fibrin: A single examiner will enrol the participants. Random allocation of the patient will be done using sequentially numbered opaque sealed envelopes. All as
Sponsors
Kirthi George
Eligibility
Inclusion criteria
Inclusion criteria: Patients with TMD Wilkes stage III, IV, V (DC TMD Criteria 2015) Patients not having relief from conservative treatment for at least 3 months with VAS score more than 5 Age group 18-65 years, regardless of gender Patients willing to give written informed consent
Exclusion criteria
Exclusion criteria: Autoimmune disorders -Benign or malignant lesion of the temporomandibular joint, Neurological disorders- Bruxism Blood disorders and coagulopathies Patients with a history of allergy or anaphylactic shock Severe malocclusion- Crowding, Anterior deep bite Patients with acute infectious disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of pain?VISUAL ANALOGUE SCALE (horizontal graded linear)Timepoint: Evaluation will be carried out at 14 days, 1 month, 2 months and 3 months post intervention. The change in VAS score [from baseline to VAS at 3 months (VAS T4)] will be considered as the primary outcome. | — |
Secondary
| Measure | Time frame |
|---|---|
| The range of mandibular motion (maximum unassisted opening (MUO), maximum assisted opening (MAO), protrusive movement (PM), right lateral excursion (RLE) and left lateral excursion (LLE)Timepoint: Evaluation will be carried out at 14 days, 1 month, 2 months and 3 months post intervention. The change in VAS score [from baseline to VAS at 3 months (VAS T4)] will be considered as the primary outcome.;Tenderness of masticatory muscles (masseter and temporalis) ? by manual palpationTimepoint: Evaluation will be carried out at 14 days, 1 month, 2 months and 3 months post intervention. The change in VAS score [from baseline to VAS at 3 months (VAS T4)] will be considered as the primary outcome.;Clicking sound and crepitusTimepoint: Evaluation will be carried out at 14 days, 1 month, 2 months and 3 months post intervention. The change in VAS score [from baseline to VAS at 3 months (VAS T4)] will be considered as the primary outcome. | — |
Countries
India
Contacts
Public ContactKirthi George
Post graduate institute of medical education and research, Chandigarh
Outcome results
None listed