Comparing personalized breathing support with standard methods to prevent lung collapse during laparoscopic abdominal surgery

Comparison of driving pressure guided individualized PEEP with conventional PEEP in preventing lung atelectasis in patients undergoing laparoscopic abdominal surgery - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/093965

Enrollment

104

Registered

2025-09-01

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: K806- Calculus of gallbladder and bile duct with cholecystitis Health Condition 3: N201- Calculus of ureter Health Condition 4: N852- Hypertrophy of uterus

Interventions

Intervention1: Driving pressure guided Individualized PEEP: Driving pressure guided Individualized PEEP will be given in ventilator settings during laparoscopic abdominal surgery while maintaining the

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for elective laparoscopic abdominal surgery, classified as ASA physical status 1 to 2

Exclusion criteria

Exclusion criteria: 1.Candidates with pre existing lung and chest related issues Like copd, asthma 2. History of pulmonary and thoracic surgery or history of mechanical ventilation within 1 month 3. Known neuromuscular dysfunction 4. Patients with contraindications of PEEP 5. BMI greater than 35

Design outcomes

Primary

Measure	Time frame
To compare postoperative lung atelectasis at 30 minutes post extubation in post anesthesia care unit using lung ultrasound score between two study groups of patient undergoing laparoscopic abdominal surgeryTimepoint: At 30 minutes of post extubation	—

Secondary

Measure	Time frame
To evaluate interoperative mechanical respiratory parameters, including peak airway pressure, peak plateau pressure, dynamic lung compliance.Timepoint: After intubation, after establishment of Pneumo peritonium and after Exsufflation of pneumo peritonium.;To evaluate intra operative HemodynamicsTimepoint: before and after intubation, after establishment of Pneumo peritonium and after Exsufflation of pneumo peritonium.;To evaluate biomarkers of inflammation in patient of laparoscopic abdominal surgeryTimepoint: Before intubation and 30 minutes after intubation.	—

Measure

Time frame

To evaluate interoperative mechanical respiratory parameters, including peak airway pressure, peak plateau pressure, dynamic lung compliance.Timepoint: After intubation, after establishment of Pneumo peritonium and after Exsufflation of pneumo peritonium.;To evaluate intra operative HemodynamicsTimepoint: before and after intubation, after establishment of Pneumo peritonium and after Exsufflation of pneumo peritonium.;To evaluate biomarkers of inflammation in patient of laparoscopic abdominal surgeryTimepoint: Before intubation and 30 minutes after intubation.

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Countries

India

Contacts

Public ContactDr Udismita Baruah

Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi

udismitabaruah@gmail.com9868996636

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026