Evaluating a Blood-Derived Gel to Improve Surgical Treatment of Urethral Narrowing Using Tissue from the Inner Cheek

The Use of Autologous Platelet-Rich Plasma Gel in Urethral Stricture Disease Undergoing Buccal Mucosal Graft Urethroplasty: An Open-Labelled Parallel Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/093954

Enrollment

Registered

2025-09-01

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N359- Urethral stricture, unspecified

Interventions

Intervention1: Autologus Paltelet Rich Plasma: Blood was taken preoperatively and processed using standard protocols at our institute and placed at graft site during Buccal Mucosal Graft urethroplas

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Urethral stricture disease undergoing Buccal Mucosal Graft Urethroplasty

Exclusion criteria

Exclusion criteria: a) Patient unfit for surgery/Anaesthesia. b) Patients with thrombocytopenia c) Patients with coagulation disorders d) Patients not giving consent

Design outcomes

Primary

Measure	Time frame
To compare effectiveness of treatment by using Validated symptom score (IPSS score) in patients undergoing Buccal Mucosal Graft Urethroplasty for Urethral stricture disease by using PRP in comparison to conventional Buccal Mucosal Graft UrethroplastyTimepoint: at 3 months and 6 months post surgery	—

Secondary

Measure	Time frame
? To assess the perioperative complication rate in two groups Timepoint: at 3,6 months;?To compare recurrence rate of stricture in two groups Timepoint: 3,6 months	—

Countries

India

Contacts

Public ContactDr Mahendra Singh

AIIMS, Jodhpur

dr.mahi1118@gmail.com9891445049

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026