In this study, in planned fullterm pregnant women undergoing cesarean section spinal anaesthesia with two different additives which to be compared administered. So the probable outcome maybe one drug is superior to another for post operative pain relief.

Comparison of intrathecal Ropivacaine with Dexmedetomidine and Ropivacaine with Fentanyl in parturients undergoing elective LSCS. A double blinded randomised clinical study - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093937

Enrollment

Registered

2025-08-29

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium

Interventions

Intervention1: Elective LSCS intrathecal administration of two different additives mixed with Ropivacaine.: We are adding Dexmedetomidine and Fentanyl to Ropivacaine to study the postoperative analges

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age group :21 to 45 years women having gestational age more than 37 weeks. 2. Elective caesarean deliveries done under Spinal Anaesthesia. 3. ASA (American Society Of Anaesthesiologists) physical status II and III.

Exclusion criteria

Exclusion criteria: 1.Refusal to Enrol for the study 2.Any contraindications for spinal anaesthesia 3.Multifetal gestation 4.Eclampsia 5.Obesity BMI more than 35kg/m2 6.Short stature 7.Uncontrolled medical illness like cardiac diseases, renal diseases and anemia

Design outcomes

Primary

Measure	Time frame
Administering intrathecal inj Dexmedetomidine with inj Ropivacaine probably has better analgesic effect when compared to intrathecal administration of inj Fentanyl with inj Ropivacaine.Timepoint: 24 hours	—

Secondary

Measure	Time frame
Compared to Fentanyl, Dexmedetomidine may provide better hemodynamic stability and risk of intra and post operative shivering is lesserTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactDr Sampritha P G

S.N.M.C and HSK hospital

rameshkoppaldr@gmail.com9845504515

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026