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Kidney Problems in ICU Patients: How Often They Happen and What They Mean

Epidemiology and Short-term Outcomes of Hospital-Acquired Acute Kidney Injury (AKI) in Critically Ill Adults: A Prospective Cohort Study - HAKI Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/08/093914
Enrollment
230
Registered
2025-08-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

Dr Y Srikanth Reddy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Hospitalized for more than 48 hours and Transferred to the Critical Care Unit (CCU)

Exclusion criteria

Exclusion criteria: 1.Pre-existing AKI- defined as an increase in serum creatinine of greater than or equal to 0.3 mg per dL from baseline within 48 hours during the hospital stay before CCU admission, or from any available prior outpatient creatinine measurements in non-hospitalized individuals 2.Chronic kidney disease (CKD), or end-stage renal disease (ESRD) patients 3.History of renal transplantation 4.Pregnant patients 5.Terminally ill patients with a life expectancy less than 48 hours 6.Patients transferred from other Intensive Care Units (ICUs) 7.Patients with less than 48 hours length of stay in the CCU

Design outcomes

Primary

MeasureTime frame
1)To determine the incidence of hospital-acquired Acute Kidney Injury (AKI) in critically ill adult patients admitted to the Critical Care Unit (CCU)Timepoint: Baseline, after 48hrs.

Secondary

MeasureTime frame
1) To identify & evaluate the risk factors for hospital-acquired Acute Kidney Injury (AKI) in critically ill adult CCU patients 2) To evaluate outcomes, including Major Adverse Kidney Events (MAKE-30 & MAKE-90), at 30- & 90-day post-discharge in critically ill adult patients with AKI 3) To compare clinical outcomes between critically ill adult patients with & without Acute Kidney Injury (AKI) in terms of i. ICU length of stay ii. Hospital length of stay iii. Mechanical ventilation days 4) To assess 30- & 90-day post-discharge mortality outcomes in non-AKI critically ill adult patients Timepoint: Baseline, after 48hrs, 30 days, 90 days.

Countries

India

Contacts

Public ContactDr Y Srikanth Reddy

Jawaharlal Institute of Postgraduation Medical Education & Research

anushacherian@gmail.com8977837656

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026