Health Condition 1: - Health Condition 2: 3- Administration
Conditions
Interventions
Intervention1: Intravenous Dexmedetomedine 0.25mcg/kg: Intravenous Dexmedetomedine 0.25mcg/kg over 10 seconds before Intravenous propofol 25percent of the calculated dose
Control Intervention1: Intrav
Sponsors
Sapthagiri Institute of Medical Sciences and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: 1 Informed consent 2 Age between 20 to 50 years. 3 ASA I and II patients . 4 Posted for elective surgery under general Anaesthesia.
Exclusion criteria
Exclusion criteria: 1 Pregnant and lactating women. 2 Patients with hypersensitivity or allergies to Dexmedetomidine, Propofol or Tramadol. 3 Diabetes, cardiovascular diseases, liver and kidney disorders, psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effectiveness of dexmedetomidine and tramadol as pre-treatment in alleviating propofol injection pain. Timepoint: Pain assessment will be done 15 seconds after injection of 25% of calculated dose.Pain severity was assessed using a McCririck and Hunter Scale - a 4-point verbal rating scale. 0 - No pain 1 - Mild pain (pain reported only in response to questioning without any behavioural signs) 2 - Moderate pain (pain reported in response to questioning and accompanied by a behavioural sign or pain reported spontaneously without questioning). 3 - Severe pain (strong vocal response or response accompanied by facial grimacing, arm withdrawal or tears). | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr Nikila D G
Sapthagiri Institute of Medical Sciences and Research Centre
Outcome results
None listed