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This study compares the effectiveness of External Oblique Intercostal Nerve Block (EOIB) and Modified Thoracoabdominal Nerve Block (M-TAPA) in managing postoperative pain and reducing opioid consumption in patients undergoing laparoscopic gallbladder removal surgery

Efficacy of External Oblique Intercostal Block (EOIB) Vs Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) for post-operative pain in Laparoscopic Cholecystectomy - A randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093882
Enrollment
110
Registered
2025-08-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Efficacy of External Oblique Intercostal Block (EOIB) Vs Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M- TAPA) for post-operative pain in Laparoscopic Cholecyst

Sponsors

Kalinga Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.American Society of Anesthesiologists (ASA) physical status I-II 2.Age 18-60 years 3.Patients posted for Laparoscopic cholecystectomy 4.Both male and female

Exclusion criteria

Exclusion criteria: 1.Local site infection 2.Drug allergy 3.Contraindication to peripheral nerve blocks 4.Pre operative hypotension (MAP less than 70) and bradycardia (HR less than 50)

Design outcomes

Primary

MeasureTime frame
To assess postoperative pain using visual analogue scale (VAS) score between the two groups at 12th hourTimepoint: 12th hour post surgery—

Secondary

MeasureTime frame
1. Total opioid consumption in postoperative period 2. Intraoperative- Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP) and, SpO2 baseline before induction. 3. Intraoperative- Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP) and, SpO2 and EtCO2 during surgery. 4. Time to the requirement of 1st dose of rescue analgesic in minutes. 5. Incidence of adverse effects like post op nausea and vomiting and sedation. Timepoint: 1. Total opioid consumption in postoperative period 2. Intraoperative- Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP) and, SpO2 baseline before induction. 3. Intraoperative- Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP) and, SpO2 and EtCO2 every 10 mins interval till the end of surgery. 4. Time to the requirement of 1st dose of rescue analgesic in minutes. 5. Incidence of adverse effects like post op nausea and vomiting and sedation.—

Countries

India

Contacts

Public ContactDr Chandra Sekhar Pradhan

Kalinga Institute of Medical Sciences

trajmohan.rao@kims.ac.in9701185818

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026