Health Condition 1: L814- Other melanin hyperpigmentation
Conditions
Interventions
Intervention1: Combination of Q switched Nd-YAG laser with 0.1% Tacrolimus ointment: patients will be given 4 sessions of QS NdYAG laser at 4 weeks interval along with tacrolimus ointment
Control Inte
Sponsors
Dr Rashmi Sarkar
Eligibility
Inclusion criteria
Inclusion criteria: All adults in the age group of 18 years and above with clinically and histologically confirmed cases of ADMH affecting the face and/or neck, with stable disease (no new lesions or increase in size of older lesions in the past 6 months) will be included.
Exclusion criteria
Exclusion criteria: 1. Pregnant or Lactating females 2. Patient having active local infection 3. Patients having history of photosensitivity 4. Patients having keloid and keloidal tendencies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients in each treatment group who achieve more than 50 percent improvement according to the Physician Global Assessment Mean change in DPASI score in both the groups at 18 weeks from baseline. Timepoint: 18 wks | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean improvement in patient satisfaction score in both the groups.Timepoint: 18 wks;Proportion of patients in each treatment group having improvement in quality of life, according to DLQI.Timepoint: 18 wks;Proportion of patients in each treatment group experiencing adverse effects during the treatment period.Timepoint: 18 wks | — |
Countries
India
Contacts
Public ContactDivya Das
Lady Hardinge Medical College
Outcome results
None listed