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To evaluate the effectiveness of one antiemetic drug versus two antiemetic drugs in preventing nausea and vomiting in patients undergoing laparoscopic gall bladder removal surgery without use of opioids.

Comparative evaluation of single agent with dual agent antiemetic regimen for post operative nausea and vomiting prophylaxis in patients undergoing laparoscopic cholecystectomy with opioid free anaesthesia. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093800
Enrollment
75
Registered
2025-08-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80-K87- Disorders of gallbladder, biliary tract and pancreas

Interventions

Intervention1: Single vs dual antiemetic prophylaxis in patients posted for laparoscopic cholecystectomy under opioid free anaesthesia: Opioid free general anaesthesia is given in all three groups wit

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 patients Age 18-65 years

Exclusion criteria

Exclusion criteria: BMI more than or equal to 35 kg per metre square Patient with history of PONV and motion sickness Patients with cardiac conduction defects and significant cardiac disease Patient who had received opioids,non steroidal antiinflamatory drugs, steroids, antiemetic agents during previous 24 hours History of allergy to therapeutic drugs used in the study History of neurobehavioral disorders Pregnancy and lactation

Design outcomes

Primary

MeasureTime frame
Incidence of post operative nausea and vomiting in first 24 hours after surgery in patients posted for laparoscopic cholecystectomy under opioid free general anaesthesia.Timepoint: at 0,0-2 ,2-6,6-12,12-24 interval hours after laparoscopic cholecystectomy under opioid free general anaesthesia.—

Secondary

MeasureTime frame
PONV using PONV scoreTimepoint: at 0,0-2 ,2-6,6-12,12-24 interval hours after laparoscopic cholecystectomy under opioid free general anaesthesia.ponv using PONVscore;Number of patients having clinically significant PONV using PONV impact scaleTimepoint: at 0,0-2 ,2-6,6-12,12-24 interval hours after laparoscopic cholecystectomy under opioid free general anaesthesia.;Time from end of surgery to requirement of rescue antiemeticTimepoint: Nil;Total consumption of antiemetic over 24 hrs post operativeTimepoint: Nil;Time taken for resolutin of PONV after administration of rescue antiemetic.Timepoint: Nil—

Countries

India

Contacts

Public ContactDr Bharti Wadhwa

Maulana Azad Medical College

drbhartitaneja@gmail.com01123239271

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026