Health Condition 1: S798- Other specified injuries of hip and thigh
Conditions
Interventions
Intervention1: Intravenous Dexmedetomidine: This group is given Subarachnoid Block and Dexmedetomidine infusion of 0.5 mcg/kg/hr is started just prior to incision and is stopped 15 minutes just prior
Sponsors
Kalinga Institute of Medical Sciences, Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective proximal femur nailing. 2. American Society of Anaesthesiologist (ASA) physical status I-III . 3. Patients aged 50 years and older (defined as ?elderly? as per WHO )
Exclusion criteria
Exclusion criteria: 1. Patients with haemodynamic instability 2. Known history of psychiatric illness , previous history of dementia , delirium, head injury 3. History of allergy to anaesthetic drugs 4. Contraindications to regional anaesthesia 5. Failed Central Neuraxial Block 6. Patients with communication or hearing or speech impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the incidence of post-operative cognitive dysfunction using Montreal Cognitive Assessment (MoCA) Score in both the groupsTimepoint: at 72 hours after surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the incidence of postoperative cognitive dysfunction using MoCA score Timepoint: 24hours pre-operatively followed by 72hours post-operatively;Time taken to first ambulation is assessed.Timepoint: 0 hours post-operatively;To evaluate correlation of C-reactive protein levels with incidence of post-operative cognitive dysfunction in both the groups .Timepoint: pre-operatively followed by post-operatively at 72 hours | — |
Countries
India
Contacts
Public ContactDr Amrita Panda
Kalinga Institute of Medical Sciences , Bhubaneswar
Outcome results
None listed