Comparing the drugs to get better pain management

A Prospective randomized comparative study evaluating the analgesic efficacy of 0.2% Ropivacaine versus 0.2% Ropivacaine with dexmedetomidine in adductor canal block combined with iPACK for total knee arthroplasty - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093605

Enrollment

Registered

2025-08-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Comparative study to evaluate analgesic efficacy by adding dexmeditomidate to inj Ropivacaine 0.2% in adductor canal block with ipack for total knee arthroplasty: Adductor canal block 2

Eligibility

Inclusion criteria

Inclusion criteria: Adults aged 25-80 years ASA physical status I?III Undergoing elective total knee replacement surgeries Willingness to participate with informed consent

Exclusion criteria

Exclusion criteria: Patient refusal to the study BMI morethan 40 Revision or bilateral knee surgeries Known allergy to local anaesthetics Neurological disorders affecting lower limb mobility Coagulopathy or on anticoagulants Patients refusing regional anaesthesia

Design outcomes

Primary

Measure	Time frame
Duration of AnalgesiaTimepoint: Duration of Analgesia	—

Secondary

Measure	Time frame
Postoperative pain scores using the NRS at rest & during movement at 2 4 6 12 24 36 & 48 hours Time of activation of first epidural as rescue analgesic Degree of motor blockade (Modified Bromage Scale) Ramsay sedation score Time to first ambulation Patient satisfaction score Incidence of side effects or complications eg hypotension urinary retention nausea vomiting motor weakness Timepoint: 2hours,4hours, 6hours, 12hours, 24hours, 36hours,& 48 hours	—

Measure

Time frame

Postoperative pain scores using the NRS at rest & during movement at 2 4 6 12 24 36 & 48 hours Time of activation of first epidural as rescue analgesic Degree of motor blockade (Modified Bromage Scale) Ramsay sedation score Time to first ambulation Patient satisfaction score Incidence of side effects or complications eg hypotension urinary retention nausea vomiting motor weakness Timepoint: 2hours,4hours, 6hours, 12hours, 24hours, 36hours,& 48 hours

—

Countries

India

Contacts

Public ContactDr Praveen Raju

Ballari Medical college and Research centre

docraghu2009@gmail.com9945434495

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026