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Comparative study of postoperative nausea and vomiting in patients undergoing laparoscopic removal of gall bladder using narcotic pain killer versus non narcotic pain killer.

Comparative randomised controlled study of PONV(postoperative nausea and vomiting) in laparoscopic cholecystectomy, opioid vs ketamine lignocaine based anesthesia - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093586
Enrollment
100
Registered
2025-08-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80- Cholelithiasis

Interventions

Intervention1: Lignocaine and Ketamine: lignocaine (loading dose with 2 mg/kg followed by 1.5 mg/kg/hr continuous infusion) and a single dose of ketamine 0.4 mg/kg given 5 minutes before estimated ext

Sponsors

Dr Haneefa Khan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) The patients who have given informed consent. 2) The Patients of ASA-American Society of Anaesthesiologists Grade I, II. 3) The Patients aged 18 -50yrs. 4) The patients who are electively scheduled for laproscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: 1) The patients who refused to participate in the study. 2) The patients with ASA Grade 3 and above. 3) Patients aged below 18 and above 50 years. 4) Vestibular disorders, pregnancy and patients with history of chemotherapy. 5) The patients with known hypersensitivity to the local anaesthetics & Opioids.

Design outcomes

Primary

MeasureTime frame
Reduced incidence of PONV(post operative nausea & vomiting) in laproscopic cholecystectomy patients without compromising on intraoperative haemodynamic stability of patient. Timepoint: 24 hours

Secondary

MeasureTime frame
Prevention Of Opioid Related Adverse Effects Timepoint: 24 hours;Early Recovery After Surgery Timepoint: 24 hours;Patients Comfort During Perioperative Period Timepoint: 24 hours;Patients Satisfaction During Perioperative Period. Timepoint: 24 hours

Countries

India

Contacts

Public ContactDr Avijit Banerjee

Peerless Hospital & B K Roy Research Centre

draviban@gmail.com6289508707

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026