Homoeopathic treatment of nnumbness, tingling, aching, and burning pain, hyperesthesia, and weakness of limbs in adults with high blood sugar.

Efficacy of individualized homeopathic medicines in the treatment of peripheral diabetic neuropathy in adults A double-blind, randomized, placebo-controlled trial with mutual antidiabetic standard care - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093559

Enrollment

142

Registered

2025-08-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E11- Type 2 diabetes mellitus

Interventions

Intervention1: Individualized homoeopathic medicines plus Standard care and Concomitant care: Intervention is planned as administering indicated homoeopathic medicines in centesimal potencies (CH). Ea

dosage and repetition depending upon the individual requirement of the cases. Patients will be advised to refrain from handling the globules or from eating, drinking, smoking or brushing their teeth w

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adults aged of 30-65 years 2. Participant of either sex or transgender. 3. person who had been diagnosed with diabetic neuropathy for at least 3 months. 4. DNE score greater than 3.

Exclusion criteria

Exclusion criteria: 1. Individuals with other neurological disorders. 2. Abnormal gait, loss of arch with multiple fractures in tarsal bones wrist, foot drop. 3. Diabetic complications (such as retinopathy or renal involvement with history of recurrent acute complaints like hypoglycaemia, keto-acidosis). 4. Self-reported immune-compromised state. 5. Tobacco chewing and/or smoking, alcoholism and/or any other form(s) of substance abuse and/or dependence. 6. Pregnant or lactating women, unstable mental health. 7. Those who requiring insulin with an HbA1c equal or more than 10. 8. Participants who had received homeopathic treatment for chronic diseases in the last 6 months or were critically ill were also excluded from the study. 9. patient not providing with written informed consent voluntarily. 10. Vulnerable population-Unconscious, non-ambulatory, too sick for consultation, differently abled, terminally ill or critically ill patients, mentally incompetent people.

Design outcomes

Primary

Measure	Time frame
Neuropathy total symptom score(NTSS-6)Timepoint: Baseline, every months up to three months	—

Secondary

Measure	Time frame
Douleur Neuropathique 4 Questions (DN4) scaleTimepoint: Baseline, every months up to three months;Diabetic Neuropathy Examination (DNE) scoreTimepoint: Baseline, every months up to three months;Measure Yourself Medical outcome Profile version 2 (MYMOP-2) scoreTimepoint: Baseline, every months up to three months;Fasting blood sugar (FBS), Postprandial blood sugar (PPBS)Timepoint: Baseline, every months up to three months;HbA1C%, lipid profile, liver enzymes (ALT, AST), urea, creatinine, urine profileTimepoint: At baseline and after three months of interventions	—

Measure

Time frame

Douleur Neuropathique 4 Questions (DN4) scaleTimepoint: Baseline, every months up to three months;Diabetic Neuropathy Examination (DNE) scoreTimepoint: Baseline, every months up to three months;Measure Yourself Medical outcome Profile version 2 (MYMOP-2) scoreTimepoint: Baseline, every months up to three months;Fasting blood sugar (FBS), Postprandial blood sugar (PPBS)Timepoint: Baseline, every months up to three months;HbA1C%, lipid profile, liver enzymes (ALT, AST), urea, creatinine, urine profileTimepoint: At baseline and after three months of interventions

—

Countries

India

Contacts

Public ContactSUBHRANIL SAHA

D N DE HOMOEOPATHIC MEDICAL COLLEGE AND HOSPITAL

asamiul504@gmail.com6290039839

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026