Comparison of efficacy of Tapentadol nasal spray vs multimodal systemic analgesia for pain relief in patient with multiple rib fracture

Comparison of efficacy of Tapentadol nasal spray vs multimodal systemic analgesia for pain control in patient with multiple rib fracture - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093546

Enrollment

Registered

2025-08-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S225- Flail chest Health Condition 2: S224- Multiple fractures of ribs

Interventions

Intervention1: intravenous tramadol, intravenous paracetamol, intravenous diclofenac: intravenous tramadol, intravenous paracetamol, intravenous diclofenac these are being used for pain control. dura

Eligibility

Inclusion criteria

Inclusion criteria: Patients with chest injury with two or more rib fracture Patients between 18-65 years of age

Exclusion criteria

Exclusion criteria: Chest injury without rib fracture or with a single rib fracture Glasgow coma scale less than 15 Patients on ventilator support Patients requiring epidural analgesia Patients leaving against medical advice or in hospital mortality Known allergy to study drug Patients with severe renal or hepatic impairment Patient refusal to participate in the study

Design outcomes

Primary

Measure	Time frame
To compare the pain scores and rescue analgesia requirement in patients receiving Tapentadol nasal spray and multimodal systemic analgesia in patients with multiple rib fracturesTimepoint: ENTIRE HOSPITAL STAY AND POST 7 DAY DISCHARGE	—

Secondary

Measure	Time frame
To compare the tolerability and side effects of the drugs used in two groups. To compare the satisfaction scores of patients receiving two types of analgesia as well as treating surgeons Timepoint: ENTIRE HOSPITAL STAY AND POST 7 DAY DISCHARGE	—

Countries

India

Contacts

Public ContactDeepak

Pandit Bhagwat Dayal Sharma Post Graduate Institute Of Medical Sciences

deepakdpk185@gmail.com8571011867

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026