Study of changes intraoperatively between 0.5 percent hyperbaric bupivacaine and 0.75 percent hyperbaric ropivacaine in spinal anaesthesia- a RCT

Study of intraoperative hemodynamic changes between 0.5 percent Hyperbaric Levobupivacaine and 0.75 percent Hyperbaric Ropivacaine in subarachnoid block- a RCT - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093543

Enrollment

Registered

2025-08-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S821- Fracture of upper end of tibia Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: HYPERBARIC ROPIVACINE : 3ml of 0.75% Hyperbaric Ropivacaine, during subarachnoid block Control Intervention1: Hyperbaric Levobupivacaine: 3ml of 0.5% Hyperbaric Levobupivacaine during s

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient posted for elective surgery under spinal anaesthesia. 2.Patients giving consent for the study 3.American Society of Anaesthesiologists (ASA) physical status I

Exclusion criteria

Exclusion criteria: Known allergy to drugs used in the study. Patients with local skin infections at the site of injection Patients with spine deformity Surgeries requiring more than 3 hrs Patients with surgical complications like intra-operative bleeding change in surgical plan, extending duration of surgery or change of anesthetic plan to General Anaesthesia(GA) due to surgical requirements

Design outcomes

Primary

Measure	Time frame
To compare the intraoperative hemodynamic changes between two groups i.e Hyperbaric Levobupivacaine versus Hyperbaric Ropivacaine in spinal anaesthesiaTimepoint: 2 years	—

Secondary

Measure	Time frame
To compare and evaluate Duration of sensory blockade Timepoint: 2 years;Duration of motor blockadeTimepoint: 2 years	—

Countries

India

Contacts

Public ContactProf Dr Lingaraj Sahu

KALINGA INSTITUTE OF MEDICAL SCIENCES (KIMS) KIIT DEEMED TO BE UNIVERSITY

lingaraj.sahu@kims.ac.in8280166501

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026