A study comparing two different stitches for closing the tummy after surgery and their effect on healing and recovery

Suturing Smarter: Closure of Midline Laparotomy Using Barbed Polydioxanone Versus Conventional Polydioxanone A Randomized Controlled Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/08/093507

Enrollment

Registered

2025-08-22

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: -

Interventions

Intervention1: Barbed group: Barbed PDS suture for continuous, knotless fascial closure Control Intervention1: Non Barbed group: Traditional monofilament suture i.e polydioxanone with continuous knot-

Eligibility

Inclusion criteria

Inclusion criteria: Previous midline incision, ventral hernia- now planned only herniorrhaphy Written informed consent

Exclusion criteria

Exclusion criteria: Emergency laparotomy Immunocompromised states Diabetes with poor glycemic control HbA1c over 8.5 Pregnant patients

Design outcomes

Primary

Measure	Time frame
Incidence of wound dehiscence or SSI within 10 postoperative daysTimepoint: Incidence of wound dehiscence or SSI within 10 postoperative days	—

Secondary

Measure	Time frame
1) Operative time for fascial closure (minutes) 2) Postoperative pain (VAS score) on POD 1, 3, 5 3) Incisional hernia at 3months, 6 months & 1 year (clinical & ultrasonographic evaluation) 4) Direct cost of suture materialTimepoint: Postoperative pain (VAS score) on POD 1, 3, 5 3) Incisional hernia at 3months, 6 months & 1 year (clinical & ultrasonographic evaluation)	—

Countries

India

Contacts

Public ContactDR LAVU JAYANTH

AIIMS MANGALAGIRI

LAVUJAYANTH@AIIMSMANGALAGIRI.EDU.IN9849511547

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026