To compare Ketoprofen and Diclofenac patches for pain control after periodontal flap surgery

Comparative evaluation of efficacy of ketoprofen and diclofenac transdermal patch in the management of postoperative pain following periodontal flap surgery - A Split mouth, Randomized Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093503

Enrollment

Registered

2025-08-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Ketoprofen patch(Ketoplast plus patch, 30mg) for 3days: 1)Patients included under the study will be divided into two groups, Group A and Group B. 2)All the surgeries will be performed b

Eligibility

Inclusion criteria

Inclusion criteria: 1)Systemically healthy patient. 2)Patient age ranging 25-60 years. 3)Periodontal pocket depth more than or equal to 5mm. 4)Patient requiring at least 2 quadrants for flap surgery. 5)Patients with good oral hygiene after scaling and root planning. 6)Presence of at least 20 natural teeth. 7)Patient willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1)The patients who are undergoing treatment with analgesics or corticosteroids during the trial period. 2)Pregnancy and lactating mothers. Smokers and alcoholic. 3)Patients with cardiovascular disease. 4)Patients with gastrointestinal bleeding or ulcers. 5)Patients with liver diseases. 6)Patients with kidney diseases. 7)Patient allergic to Diclofenac and Ketoprofen.

Design outcomes

Primary

Measure	Time frame
To compare and evaluate the efficacy of Ketoprofen and Diclofenac transdermal patch in the management of postoperative pain following periodontal flap surgery.Timepoint: Every hour upto 8hours	—

Secondary

Measure	Time frame
1)To evaluate the efficacy of Diclofenac transdermal patch in reducing postoperative pain following periodontology flap surgery. 2)To evaluate the efficacy of Ketoprofen transdermal patch in reducing postoperative pain following periodontology flap surgery. 3)To compare the efficacy of Ketoprofen and Diclofenac transdermal patch in reducing postoperative pain following periodontal flap surgery. 4)To evaluate the adverse reaction (if any) following the use of Diclofenac and Ketoprofen transdermal patch. Timepoint: Every hour upto 8hours	—

Measure

Time frame

1)To evaluate the efficacy of Diclofenac transdermal patch in reducing postoperative pain following periodontology flap surgery. 2)To evaluate the efficacy of Ketoprofen transdermal patch in reducing postoperative pain following periodontology flap surgery. 3)To compare the efficacy of Ketoprofen and Diclofenac transdermal patch in reducing postoperative pain following periodontal flap surgery. 4)To evaluate the adverse reaction (if any) following the use of Diclofenac and Ketoprofen transdermal patch. Timepoint: Every hour upto 8hours

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Countries

India

Contacts

Public ContactJaswanth sanam G

KVG Dental College and Hospital

prakashpaipai2014@gmail.com9845156405

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026