FindTrial
Sign In

Comparison of two drugs for prevention of post spinal hypotension in pregnant females

Comparison of Mephentermine and Norepinephrine infusions for prevention of post-spinal hypotension during elective caesarean delivery:a randomised,double-blind trial. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093464
Enrollment
100
Registered
2025-08-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: MEPHENTERMINE INFUSION at 600 microgram/ml intraoperatively: Prophylactic mephentermine infusion in prevention of post spinal hypotension Control Intervention1: Mephentermine vs norepin

Sponsors

Dr Ananya
Lead Sponsor
Dr Akhileshwar
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Willing to participate, term uncomplicated singleton pregnancy, ASA1 and ASA2 Status, elective caesarean delivery

Exclusion criteria

Exclusion criteria: Refusal to participate, emergency c-section,multiple gestation, maternal or fetal disorders, absolute or relative contraindications to spinal anesthesia

Design outcomes

Primary

MeasureTime frame
Effect on umbilical artery pH Timepoint: Post delivery of placenta( at baseline)—

Secondary

MeasureTime frame
Hemodyanamic parameters ( HR SBP DBP MAP SPO2) APGAR score at 1 & 5 minutes Incidence of maternal hypotension Volume of infusion required Incidence of maternal complications if anyTimepoint: Pre intra & post delivery during spinal anesthesia (at baseline)—

Countries

India

Contacts

Public ContactDr Ananya

Indira Gandhi Institute of Medical Sciences, Patna

9.akhileshwar@gmail.com9835186989

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026