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Evaluating Various Doses of Dexmedetomidine with Spinal Anaesthesia for Lower Limb Surgeries

COMPARISON OF DIFFERENT DOSES OF DEXMEDETOMIDINE AS ADJUVANT TO HYPERBARIC BUPIVACAINE IN SPINAL ANAESTHESIA FOR LOWER LIMB ORTHOPAEDIC SURGERIES - nil

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093458
Enrollment
99
Registered
2025-08-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: dexmedetomidine: group I will receive 3.0 ml of 0.5 percentage heavy bupivacaine (15 mg) with 0.5 ml of dexmedetomidine (5microgram) intrathecally. Group II will recieve 3.0 ml of 0.5

Sponsors

Government Multi Speciality Hospital
Lead Sponsor
government multispeciality hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1)Age group 18 to 60 years 2)ASA physical status grade I and grade II 3)Weight 50 to 90 kg 4)Height 150 to 180 cm 5)Patients giving consent for the study

Exclusion criteria

Exclusion criteria: 1)Patients with any contraindication to regional anaesthesia 2)Patients with a history of significant co existing diseases like uncontrolled diabetes , uncontrolled hypertension, ischaemic heart disease, recent myocardial infarction, heart block, impaired renal functions and severe liver disease. 3)Patients with spine deformities like Kyphoscoliosis, Scoliosis etc. 4)Patient with a history of allergy to the drugs to be used. 5)Patient on alpha2 agonist or antagonist therapy. 6)Expected duration of surgery more than 2.5 hours

Design outcomes

Secondary

MeasureTime frame
1)To determine the onset and duration of sensory and motor blockade 2)To study the effect on haemodynamic parameters. 3)To study side effects, if any.Timepoint: 12 Hours

Primary

MeasureTime frame
To determine duration of analgesiaTimepoint: 12 Hours

Countries

India

Contacts

Public ContactDr Vineet Kaur

Government Multi Speciality Hospital - 16, CHANDIGARH

sanjeevsabhayata@gmail.com09814683689

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026