Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Conditions
Interventions
Intervention1: levothyroxine: pre dinner administration of levothyroxine 1 hour before dinner
Control Intervention1: Levothyroxine: Pre breakfast administration of levothyroxine 1 hour before breakfas
Sponsors
Indira Gandhi Medical college and research institute
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosed with hypothyroidism and patient who are taking thyroid hormone replacement therapy for 3 months continuously prior to the study.
Exclusion criteria
Exclusion criteria: History of thyroid surgery or radioactive iodine treatment. Presence of significant comorbidities (e.g., severe cardiovascular disease, uncontrolled diabetes).Use of medications that interfere with levothyroxine pharmacokinetic property and pregnant women and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparative effectiveness of different timing strategies using serum TSH levelTimepoint: Baseline, week 12 and week 24 | — |
Secondary
| Measure | Time frame |
|---|---|
| Detailed analysis of adherence patterns between different timing regimens and comprehensive documentation of adverse effects or drug interactions Timepoint: Baseline, week 12 and week 24 | — |
Countries
India
Contacts
Public ContactRamya.V
Indira Gandhi medical college and research institute
Outcome results
None listed