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A Study to Monitor Pressure in Injured Limbs and Its Link with Blood Tests to Help Diagnose Compartment Syndrome

Co-relation of serial monitoring of intra-compartmental pressure with lab parameters in clinically diagnosed compartment syndrome - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/08/093410
Enrollment
30
Registered
2025-08-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M796- Pain in limb, hand, foot, fingersand toes

Interventions

Intervention1: Nil: Nil Intervention2: NIL: NIL

Sponsors

Rakesh Dhaka
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 65 years. 2. Patients presenting after 12 hours of trauma or vascular injury to the leg (tibia shaft) or forearm. 3. Patients with clinical signs suggestive of acute compartment syndrome. 4. Confirmed intra-compartmental pressure greater than 30 mmHg.

Exclusion criteria

Exclusion criteria: 1. Patients with open wounds. 2. Patients with polytrauma. 3. Patients with chronic kidney disease. 4. Patients with pre-existing peripheral vascular disease, muscle disorders, or peripheral neuropathy. 5. Prior history of compartment syndrome or prior limb surgery. 6. Compromised collateral circulation.

Design outcomes

Primary

MeasureTime frame
Correlation between intra-compartmental pressure and laboratory parameters including serum CPK, serum lactate, CRP, potassium, arterial pH, and urine myoglobin in patients with acute compartment syndrome. Timepoint: At admission (0 hours), 24 hours, Day 3, and Day 7

Secondary

MeasureTime frame
Evaluation of the trend of lab parameters over time and their predictive value in diagnosing and monitoring acute compartment syndrome. Timepoint: At admission (0 hours), 24 hours, Day 3, and Day 7

Countries

India

Contacts

Public ContactRakesh Dhaka

All India Institute of Medical Sciences, Raipur

drbikramkar@gmail.com8599867036

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026