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assessment of efficacy of ayurvedic toothpaste in reducing Dentinal hypersensitivity

Assessment of the efficacy of Yashtimadhvadi Pratisarna (Toothpaste) in reducing Dantaharsha (Dentinal Hypersensitivity)-A Clinical and Scanning Electron Microscopic Study - NIL

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093396
Enrollment
60
Registered
2025-08-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K038- Other specified diseases of hard tissues of teeth

Interventions

None listed

Sponsors

Government Ayurved College Nagpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients having dentinal hypersensitivity at least in 2 teeth, having minimum 16 natural teeth free of large restoration or prosthetic crown, at least two teeth showing painful response using dental explorer

Exclusion criteria

Exclusion criteria: Teeth with severe caries, faulty restoration, prosthetic crown, chipping, fracture, symptoms of pulpal damage Participants who has taken long term analgesic therapy within 30 days before the start of the study Participants who have undergone any treatment for dentinal hypersensitivity in past 3 months Participants with ongoing orthodontic therapy Participants with history or presence kidney disorder, kidney stones, eating disorders, uncontrolled gastro-oesophageal reflux disease, excessive exposure to acids or any other systemic condition that predisposes to dentinal hypersensitivity Severe Periodontal disease characterized by extensive tooth mobility and or extensive alveolar bone loss involving 10 or more teeth Women who are pregnant or lactating

Design outcomes

Primary

MeasureTime frame
Reduction in dentinal hypersensitivity (Dantaharsha) as measured by Visual Analog Scale (VAS) scores after application of Yashtimadhwadi Pratisarana. Evaluation of changes in clinical symptoms (cold, sweet, sour stimuli response)Timepoint: At baseline and after 4 weeks

Secondary

MeasureTime frame
Evaluation of dentinal tubule occlusion through SEM analysis before and after interventionTimepoint: Baseline (Day 0) and after completion of intervention (Week 4).

Countries

India

Contacts

Public ContactDr. Sarika Palve
hariumale58@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026