Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1 Patients aged greater than 18years with American Society of Anesthesiologists grade 2 planned for major electiveoncologicalsurgery 2 Patients on RAAS inhibitors
Exclusion criteria
Exclusion criteria: 1 patients who are on multiple antihypertensives excluding ACEIs and ARBs 2 Emergency or unplanned surgeries 3 Day care or minor procedures 4 Patients with severe renal dysfunction 5 Patient with EF less than 35 percent 6 uncontrolled hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To record perioperative management strategy for patients on RAAS inhibitors.Timepoint: On the day of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To record the percentage of hypertensive patients receiving RAAS inhibitorsTimepoint: The no 1 secondary outcome will be recorded at the end of the study;To note incidence of intraoperative hypotensionTimepoint: will be assessed during the surgery;To note the requirement of vasoactive agentsTimepoint: will be assessed during the surgery;To evaluate for intraoperative and postoperative blood pressure changes if preoperatively bridging done with alternative antihypertensive agentTimepoint: will be assessed during the surgery;To note intraoperative blood loss and the amount of blood products transfusedTimepoint: The postoperative blood pressure changes will be assessed for a period of 24 hours at time points immediately after shifting to PACU then after 1 hour 4 hours 8 hours 12 hours and 24 hours;To note the episodes of hypotension /hypertension intraoperativelyTimepoint: will be assessed during the surgery | — |
Countries
India
Contacts
Public ContactDr Vaidehi Mane
Tata Memorial Hospital
Outcome results
None listed