Role of Homoeopathic Medicines in the treatment of Sub-Clinical Hypothyroidism

Evaluating The Effectiveness Of Individualized Homoeopathic Medicines VS Thyroidinum 3X In Treatment Of Sub-Clinical Hypothyroidism: An Open Label Randomized Control Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093364

Enrollment

Registered

2025-08-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E03- Other hypothyroidism

Interventions

Intervention1: Individualized Homoeopathic Medicines: Individualized homoeopathic medicines will be administered in the centesimal potencies Selected according to homoeopathic principles. The doses an

Eligibility

Inclusion criteria

Inclusion criteria: 1. Both sexes of age group above 18 years and below 60 years 2. Patients with newly diagnosed sub clinical hypothyroidism (elevated TSH levels but T3 and T4 are within normal limit) with or without anti TPO antibody.

Exclusion criteria

Exclusion criteria: 1. Sub-clinical hypothyroidism patient?s sufferings from any life-threatening illness, mental illness who are terminally ill, under immunosuppressive treatment or self-reported immune-compromised state. 2. Patients of malignancy or too sick for consultation. 3. Patient on substance abuse. (Drugs/Alcohol/Smoking). 4. Females who are in pregnancy and lactating period.

Design outcomes

Primary

Measure	Time frame
Comparison of Effectiveness: The trial is expected to reveal individualized homoeopathic medicines (GROUP A) yield a significant reduction in serum TSH levels. This outcome would support the hypothesis that homoeopathic interventions may effectively in sub clinical hypothyroidism.Timepoint: 11 months	—

Secondary

Measure	Time frame
It is expected that T3 and T4 levels will remain within their normal reference range and Anti TPO antibody levels will also starts moving towards the normal reference range.Timepoint: 11 months;This study expected to identify the most effective homoeopathic medicines for the management of subclinical hypothyroidism.Timepoint: 11 months;It is expected that there will be symptomatic improvement assess through modified naranjo criteria along with general well-being, without any substantial medicinal adverse effects.Timepoint: 11 months	—

Measure

Time frame

It is expected that T3 and T4 levels will remain within their normal reference range and Anti TPO antibody levels will also starts moving towards the normal reference range.Timepoint: 11 months;This study expected to identify the most effective homoeopathic medicines for the management of subclinical hypothyroidism.Timepoint: 11 months;It is expected that there will be symptomatic improvement assess through modified naranjo criteria along with general well-being, without any substantial medicinal adverse effects.Timepoint: 11 months

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Countries

India

Contacts

Public ContactDr Honey

Dr B R Sur Homoeopathic Medical College,Hospital And Research Centre

shmc.thyroidclinic@gmail.com9871347553

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026