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Does Taking Pregabalin Before Surgery Help With Anaesthesia and Recovery for those who receiving General Anesthesia

Effect of Oral Pregabalin Premedication on Perioperative Anesthesia Outcomes in Patients Undergoing Surgery Under General Anesthesia: A Double-Blind Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093322
Enrollment
68
Registered
2025-08-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: oral pregabalin: In these patients, oral pregabalin 75mg will be pre-medicatd at two occasions, one at prior night and other at morning approximately 2 hours prior to shifting to OT for

Sponsors

Pondicherry Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ? ASA I and II ( American society of Anesthesiologist classification ) ? Patient undergoing elective surgery under general anaesthesia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
To compare postoperative pain using NRS rating scale between oral pregabalin group vs placebo in patient undergoing surgery under general anaesthesiaTimepoint: It is assessed for first 24 hours postoperative period. Assessed postoperative period at baseline,30 minutes ,1 hour,2 hours,4 hours,8 hours,12 hours,24 hours at the end of surgery

Secondary

MeasureTime frame
To compare Pre-operative anxiety score using APAIS Stress response to laryngoscopy & intraoperative hemodynamics Postoperative recovery using Aldrette scoring Postoperative sedation between two groups using Ramsay sedation score. Timepoint: Assessed postoperative period at baseline,30 minutes ,1 hour,2 hours,4 hours,8 hours,12 hours,24 hours at the end of surgery

Countries

India

Contacts

Public ContactDR JAYABHARATHI K V

Pondicherry Institute of Medical Sciences

ramyavel1988@gmail.com9487630425

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026