A study comparing how well Propolis (a natural bee product) works compared to Triamcinolone acetonide (a commonly used steroid medicine) when applied to the mouth to treat painful symptoms of oral lichen planus. Participants were randomly given one of the two treatments to see which worked better.

A Comparative Evaluation of Clinical Efficacy of Topical application of Propolis with triamcinolone acetonide in the management of symptomatic oral lichen planus: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093309

Enrollment

Registered

2025-08-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K137- Other and unspecified lesions of oral mucosa

Interventions

Intervention1: Topical propolis gel: Oral lichen planus Patients in Group I will be given Topical Propolis to apply on the affected site 3 times a day for 15 days The active treatment duration for eac

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients with clinically diagnosed atrophic/erosive OLP(based on modified WHO clinical criteria, 2003) 2 Individuals willing to be a part of the study, who sign the informed consent form, and who find it convenient to appear for follow-ups as required by the study. 3 Patients who had not used systemic or topical glucocorticosteroids for at least the past 2 weeks 4 Patients who agree not to use any other medication such as analgesics and Anesthetics in either topical form or systemic form during the study.

Exclusion criteria

Exclusion criteria: 1 Patients with lichenoid lesions thought to arise as a hypersensitivity reaction to drugs and dental materials 2 Patients on long-term glucocorticosteroid therapy 3 Pregnant and lactating female patients 4 Patients allergic to bee products

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of topical propolis in comparison with topical triamcinolone acetonide in symptomatic oral lichen planus in following parameters 1. Pain 2. Erythema and ulceration 3. Side effects Timepoint: The active treatment duration for each group will be for a period of 15 days. The patients will be recalled and scheduled for an appointment on 7th and 15th day and the clinical evaluation will be done and recorded.	—

Measure

Time frame

To evaluate the efficacy of topical propolis in comparison with topical triamcinolone acetonide in symptomatic oral lichen planus in following parameters 1. Pain 2. Erythema and ulceration 3. Side effects Timepoint: The active treatment duration for each group will be for a period of 15 days. The patients will be recalled and scheduled for an appointment on 7th and 15th day and the clinical evaluation will be done and recorded.

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Sneha Sarang

Sinhgad dental college and hospital, Pune

drmaheshschavan@gmail.com9823623445

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026