Early Physiotherapy exercises to treat the knee joint bleed in individuals with abnormal bleeding disorder in settings with less resources.

Early Physical therapy intervention following acute knee joint bleed in persons with Haemophilia in resource limited settings.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093301

Enrollment

Registered

2025-08-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D66- Hereditary factor VIII deficiency Health Condition 2: D67- Hereditary factor IX deficiency

Interventions

Intervention1: Hold -relax technique: During the Hold-relax intervention, the limb will be taken to the end of the available range and the patient instructed to ?hold? the position for 10 seconds whil

Eligibility

Inclusion criteria

Inclusion criteria: Severe Haemophilia A or B, Patients with a unilateral acute knee joint bleed

Exclusion criteria

Exclusion criteria: Haemophilia A and B with inhibitor Fixed flexion deformity in the knee joint before the bleed Previous surgeries including TKR, THR, osteotomies Muscle haematomas or other joint bleeds on the same lower limb

Design outcomes

Primary

Measure	Time frame
Knee Range of motion Timepoint: Pre-bleed Day of joint bleed 14 days post- bleed 3 month follow-up	—

Secondary

Measure	Time frame
Muscle power ? Modified Oxford scale for Manual Muscle testing, Dynamometer. Joint Health ? Haemophilia joint health score (HJHS) Ambulation ? Functional Mobility Scale (FMS) Pain ? Visual Analogue Scale (VAS score) Swelling?Circumferential measurement using inch tape. Timepoint: Pre-bleed Day of joint bleed 14 days post- bleed 3 month follow-up	—

Countries

India

Contacts

Public ContactMerlyn R

Christian Medical College Vellore,

andrewb@cmcvellore.ac.in09489590360

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026