Treatment of thin gums for preventing gum recession and loss of teeth by increasing gum thickness

Gingival phenotypic modification using recombinant human fibroblast growth factor -2 impregnated scaffold - A randomised clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093282

Enrollment

Registered

2025-08-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Intervention: Recombinant human fibroblast growth factor impregnated collagen scaffold will be used as soft tissue substitute for gingival phenotypic modification of thin gingival pheno

Eligibility

Inclusion criteria

Inclusion criteria: Thin gingival phenotype Mandibular anterior region with respect to central incisors FMBS less than 20 FMPS less than 20

Exclusion criteria

Exclusion criteria: Smokers Tobacco users Pregnancy Lactating mothers Not available for 12 months follow up Unwilling for periodic recall every 3 months

Design outcomes

Primary

Measure	Time frame
Changes in gingival soft tissue height Changes in keratinised tissue width Mean root coverage Complete root coverage Visual analog scale Patient reported outcome measuresTimepoint: Baseline, 3 Months, 6 Months, 9 Months, 12 Months	—

Secondary

Measure	Time frame
Patient satisfaction Incidence of complicationsTimepoint: 0,3,6,9,12 months	—

Countries

India

Contacts

Public ContactDr Saravanan SP

Army Dental Centre Research Referral Delhi

saravananacademics@gmail.com9637110906

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026