None listed
Conditions
Interventions
None listed
Sponsors
Vitreo Retinla Socirty of India (VRSI)
Eligibility
Inclusion criteria
Inclusion criteria: Individuals diagnosed with RPwill be includedfrom 9 centres by experienced retina specialist with expertise in management of IRDs. The diagnosis will be based on deep phenotyping including comprehensive ophthalmic examination, retinal multimodal imaging and electrophysiology wherever available.Patients presenting with nyctalopia, visual field loss and/or decreased vision, and having diffuse and/or widespread retinal pigment epithelial degeneration, arterial narrowing, disc pallor, and evidence of generalised rod and cone involvement will be diagnosed as RP
Exclusion criteria
Exclusion criteria: a) Individuals with non-genetic retinal disorders will not be included. b) Individuals with IRDs other than RP will not be included. c) Participants who refuse to or are unable to provide informed consent for genetic testing will not be included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)This study will provide a comprehensive, uniform and prospective phenotypic data using newer multimodal imaging techniques. This will depict the varied clinical presentation of RP in Indian population. 2)This study will provide the prevalence of disease causing genetic variants for RP in Indian population usinga uniform genetic testing method i.e Whole exome Sequencing or WES by a single certified service provider (Medgenome Labs Pvt. Ltd., Bengaluru, India). Timepoint: 36 week | — |
Secondary
| Measure | Time frame |
|---|---|
| NATimepoint: NA | — |
Countries
India
Contacts
Public ContactRiya Sharma
Dr. Agarwal Group of Eye Hospitals
Outcome results
None listed