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To compare two different modalities in the treatment dark circle around eye

Comparison of 10 percent trichloroacetic acid and 35 percent glycolic acid peel in the treatment of periorbital hyperpigmentation - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093240
Enrollment
60
Registered
2025-08-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 10 % trichloroacetic acid peel: 1.Patients will be made to lie down in a reclining position. A postauricular patch test will be performed on each patient 15 minutes prior to the peeling

Sponsors

Dr Baba Saheb Ambedkar medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patient age 18-60 years attending the outpatient department clinically diagnosed as periorbital hyperpigmentation and are willing to participate in the study after giving informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients on topical steroid or systemic treatment for POH In the past 1 month. 2.Patients with photosensitive disorder/photosensitizing drug 3.Inflammatory dermatoses on the face 4.Patients with unilateral POH 5.Patients with history of keloid scaring 6.Pregnancy and lactation 7.Active viral/bacterial/infection on face

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of 10% trichloroacetic acid peel and 35% glycolic acid peel in administered every three weeks for four sessions in the treatment of periorbital hyperpigmentation (aged 18-60) as assessed by dermoscopic and physician?s global assessment at pre- and post-12-week follow-up.Timepoint: 0,3,6,9 and 12 weeks follow up

Secondary

MeasureTime frame
?To compare the safety of 10% trichloroacetic peel and 35% glycolic acid peel in patients studied. ? To evaluate physician global assessment feature in clinical subtype of periorbital hyperpigmentation in patient included this study. Timepoint: 0,3,6,9 and 12 weeks follow up

Countries

India

Contacts

Public Contactdr Vivek sagar

dr baba saheb ambedker medical college and hospital

viveksagar_sagar@yahoo.co.in9210338647

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026