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Intravenous crystalloid fluid administration after spinal anaesthesia to prevent fall in blood pressure during perioperative management of pregnant patients undergoing elective lower segment caesarean section by randomized control trial.

Optimization of crystalloid co-loading speed to stabilize haemodynamics in patient undergoing elective Lower Segment Caesarean section under spinal anaesthesia: A Randomized Control Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093239
Enrollment
68
Registered
2025-08-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: GROUP A -INTERVENTION 16 GAUGE INTRAVENOUS CANNULA WITH PRESSURE OPTIMIZATION OF CRYSTALLOID CO LOADING.: IN GROUP A OPTIMIZATION OF CRYSTALLOID FLUID SPEED WILL BE DONE BY CONSTANT APP

Sponsors

VEER CHANDRA SINGH GARHWALI GOVERNMENT ISTITUTE OF MEDICAL SCIENCE AND RESEARCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant patient aged 20 to 30 years AMERICAN SOCIETY OF ANAESTHESIOLOGISTS ASA Grade 2 Women with visible vein in dorsum of preferably left hand Women with no comorbid condition

Exclusion criteria

Exclusion criteria: BMI more than 30 Poorly visible superficial veins on dorsum of hand Hb less than 10g per dl Pregnancy induced hypertension Eclampsia Foetal distress Antepartum haemorrhage. Incision to delivery time more than 10 minutes Height less than 150 cm Weight less than 40 kg Patient with deranged coagulation profile Patient with spinal deformity Patient refusal to participate in the study

Design outcomes

Primary

MeasureTime frame
To assess effect of optimization of intravenous crystalloid co loading to prevent maternal hypotension in patient undergoing elective LSCS under spinal anaesthesia.Timepoint: During perioperative period patient mean arterial pressure, systolic and diastolic blood pressure, heart rate, oxygen saturation and perfusion index will be monitored with ECG NIBP AND PULSE OXIMETRY from baseline to every 2 minutes till 30 minutes after spinal anaesthesia. Time of 20 ml per kg of crystalloid ringer lactate co loading will be noted in both the groups after spinal anaesthesia during perioperative period.

Secondary

MeasureTime frame
To calculate the requirement of vasopressor ephedrine 3mg bolus and anticholinergic drug atropine 0.6 mg during peri-operative period to prevent the maternal hypotension. Timepoint: Time of administration of intravenous ephedrine 6mg bolus will be noted whenever mean arterial pressure falls 20 or more than 20 percent of baseline in spite of crystalloid co loading during perioperative period. Time of administration of iv injection 0.6 mg bolus whenever the heart falls below 60 bpm after spinal anaesthesia.;To document the side effects of crystalloid co loadingTimepoint: Side effects such as crepitations in lungs and breathlessness will be noted during any time during perioperative and postoperative period.;To study the APGAR score of new bornTimepoint: APGAR score will be noted at 1 and 5 minutes after caesarean delivery under spinal anaesthesia.

Countries

India

Contacts

Public ContactDR SATYENDRA YADAV

VEER CHANDRA SINGH GARHWALI GOVERNMENT INSTITUTE OF MEDICAL SCIENCE AND RESEARCH VCSGGIMSR

shubham2016joshi@gmail.com9760123604

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026