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Comparative evaluation of perioperative subconjunctival triamcinolone acetonide injection versus postoperative topical prednisolone following phacoemulsification for prevention of intra-ocular inflammation.

Comparative evaluation of perioperative subconjunctival triamcinolone acetonide injection versus postoperative topical prednisolone for prevention of intra-ocular inflammation following phacoemulsification - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093238
Enrollment
140
Registered
2025-08-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H259- Unspecified age-related cataract

Interventions

Intervention1: Subconjunctival triamcinolone acetonide injection: Subconjunctival triamcinolone acetonide suspension 0.5 ml at a concentration of 40mg/ml injection given during cataract surgery for re

Sponsors

School of medical sciences and research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients eligible for cataract surgery under peribulbar anesthesia. 2. Patients with uneventful cataract surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with uncontrolled diabetes mellitus, or glaucoma, patients with a prior history of uveitis, and patients on systemic anti-inflammatory treatment. 2. Patients with corneal diseases, infectious ocular lesions, and high myopes. 3. Patients with existing retinal abnormalities. 4. Patients with complicated cataract surgery and prior ocular surgery. 6. Patients with documented allergy to triamcinolone acetonide. 7. Patients not responding to SCTA injection given during surgery.

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of subconjunctival triamcinolone acetonide suspension 0.5 ml at a concentration of 40mg/ml injection given during cataract surgery for reducing post-operative intra-ocular inflammation.Timepoint: Day 1, 7, 30, 90

Secondary

MeasureTime frame
To evaluate the efficacy of postoperative 1 % prednisolone eye drops in preventing intraocular inflammation following phacoemulsification.Timepoint: Day 1, 7, 30, 90;To compare the visual acuity, contrast sensitivity and steroid response, in cases of subconjunctival triamcinolone with the topical prednisolone eye drops in phacoemulsification. Timepoint: Day 1, 7, 30, 90

Countries

India

Contacts

Public ContactDr Abha Gahlot

school of medical sciences and research

abha.gahlot@sharda.ac.in07388270452

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026