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Comparing low vs high breathing support settings on lung stress and breathing function in patients with chest injuries during surgery.

Effect of low positive end expiratory pressure (PEEP) vs recruitment followed high PEEP on mechanical power and respiratory mechanics in patients with blunt thoracic trauma undergoing non thoracic surgery: A randomised control trial. - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093215
Enrollment
60
Registered
2025-08-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Recruitment followed High PEEP. Duration: Recruitment for 30 seconds, High PEEP throughout the surgery: Recruitment will be done by sustained inflation technique, in which a continuous

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults with blunt thoracic trauma undergoing non thoracic surgery under general anaesthesia with mechanical ventilation.

Exclusion criteria

Exclusion criteria: a) Patient refusal to participate in the study b) Known COPD or other chronic lung diseases. c) Patients with penetrating thoracic trauma. d) Pre existing cardiac dysfunction. e) Patients undergoing thoracic or cardiac surgery. f) Presence of uncontrolled arrhythmias or significant hemodynamic instability. g) Moderate to severe traumatic brain injury. h) Pregnancy I) Patients already intubated and ventilated for more than 24 hours prior to surgery

Design outcomes

Primary

MeasureTime frame
Mechanical power differences between low PEEP and recruitment followed high PEEP groups during intra operative ventilationTimepoint: After Induction, every 30 minutes and at the end of surgery.

Secondary

MeasureTime frame
To assess differences in respiratory mechanicsTimepoint: After induction, every 30 minutes and at the end of surgery.;To evaluate oxygenationTimepoint: After induction, every 30 minutes and at the end of surgery.;To compare hemodynamic effectsTimepoint: After induction, every 30 minutes and at the end of surgery.;To assess post operative pulmonary complicationsTimepoint: Upto 48 hours after surgery

Countries

India

Contacts

Public ContactDr. Abhishek Singh

AIIMS New Delhi

bikunrs77@gmail.com8287652624

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026