Effect of Ondansetron on blood pressure during cesarean delivery under spinal anesthesia

Comparison of the effect of different doses of ondansetron on spinal anesthesia induced hypotension in lower segment caesarean section: A double blinded randomized controlled study. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093209

Enrollment

180

Registered

2025-08-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: ondansetron 4mg: 4 mg ondansetron a selective serotonin antagonist diluted to 10 ml NS injected IV at the same time when spinal anesthesia is perform. The effect on systolic blood pre

Eligibility

Inclusion criteria

Inclusion criteria: 1. surgery under spinal anaesthesia. 2. elective lower section caesarian section. 3. ASA physical status II

Exclusion criteria

Exclusion criteria: 1. patient refusal 2. multiple pregnancy. 3. history of drug allergy 4. with history of cardiac disease. 5. presented with PIH and Gestational diabetes.

Design outcomes

Primary

Measure	Time frame
To determine effect of different doses of ondansetron in reducing incidence of spinal anesthesia induced hypotension during cesarean section.Timepoint: Baseline, every 5 minutes till closure of abdominal wound	—

Secondary

Measure	Time frame
nilTimepoint: nil	—

Countries

India

Contacts

Public ContactKenjom padu

Tomo riba institute of health and medical sciences

drdusulalin@gmail.com7367967439

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026