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A Study on IL6 and TNFalpha in Painful Tooth Pulp and How These Inflammation Signals Differ in Diabetic and Non Diabetic People

Differential Expression Of IL6 And TNF Alpha In Symptomatic Pulpitis A Comparative Study In Diabetic And Non Diabetic Individuals - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/08/093200
Enrollment
70
Registered
2025-08-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Intervention5: Nil: Nil Intervention6: Nil: Nil Intervention7: IL 6 and TNF aplha: nil Intervention8: Ni

Sponsors

Kanukurthi Meghana
Lead Sponsor
MNR dental college
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1)Medical Condition with Nondiabetic and type 2 Diabetic patients 2)Patients diagnosed with symptomatic pulpitis 3)Positive response to cold test 4)Teeth with adequate pulpal blood volume for biomarker analysis. 5)Willingness to Participate

Exclusion criteria

Exclusion criteria: 1)Systemic Conditions Affecting Study Outcomes such as hyperparathyroidism, hyperthyroidism, hepatic or chronic renal disease. 2)Immunocompromised conditions 3)Pregnancy 4)Medication Use That Could Influence Inflammation levels 5)Negative response to cold test

Design outcomes

Primary

MeasureTime frame
to evaluate levels of IL6 and TNF Alpha in type 2 diabetic and non diabetic pulpal blood.Timepoint: 8 Weeks—

Secondary

MeasureTime frame
nilTimepoint: nil—

Countries

India

Contacts

Public ContactKanukurthi Meghana

MNR Dental college and Hospital

vijetha.mds@gmail.com8096153333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026