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Evaluating kidney functions in ICU patients with no kidney disease and its clinical outcomes.

Incidence of augmented renal clearance and its effect on clinical outcomes of critically ill patients admitted in intensive care unit. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/08/093183
Enrollment
180
Registered
2025-08-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N08- Glomerular disorders in diseases classified elsewhere

Interventions

Intervention1: Nil: Nil

Sponsors

Postgraduate Institute of Medical Education and ResearchChandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients admitted to the Main ICU 1. Without AKI 2. AKI with KDIGO stage 1 or 2 at presentation will be enrolled (as KDIGO 1 and 2 are rapidly reversible forms of AKI).

Exclusion criteria

Exclusion criteria: 1. Patients with ICU stay less than 24 hours. 2. Patients with chronic kidney disease, with or without RRT. 3. Patients with history of prolonged immobilization, obstetric patients, patients with evidence of rhabdomyolysis, AKI (KDIGO stage 3), patients who already received RRT prior to ICU admission.

Design outcomes

Primary

MeasureTime frame
Incidence of early (on admission) or late (5th day) ARC in critically ill adult patientsTimepoint: On admission and 5th day.

Secondary

MeasureTime frame
1. To correlate the CrCl measured using urine creatinine at 8-hour urine collection & serum creatinine with calculated CrCl using other methods: Modified Cockgroft Gault formula, 4- variable Modification of Diet in Renal Disease (MDRD-4) equation & Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). 2. Clinical outcomes in patients with ARC on admission (early) or late ARC (day 5) such as days of mechanical ventilation, requirement of vasopressor/inotrope, length of stay (LOS) in ICU & mortality. 3. Incidence of patients with ARC on admission developing acute kidney injury (AKI) with or without requirement of renal replacement therapy (RRT) during ICU stay, as defined by Kidney Disease: Improving Global Outcome (KDIGO) classification. 4. Factors affecting incidence of ARC. Timepoint: At day 1,day 5 & day of discharge

Countries

India

Contacts

Public ContactNeeru Sahni

Postgraduate Institute of Medical Education and Research,Chandigarh

neerunalin@yahoo.com9872646106

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026