Health Condition 1: N08- Glomerular disorders in diseases classified elsewhere
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All adult patients admitted to the Main ICU 1. Without AKI 2. AKI with KDIGO stage 1 or 2 at presentation will be enrolled (as KDIGO 1 and 2 are rapidly reversible forms of AKI).
Exclusion criteria
Exclusion criteria: 1. Patients with ICU stay less than 24 hours. 2. Patients with chronic kidney disease, with or without RRT. 3. Patients with history of prolonged immobilization, obstetric patients, patients with evidence of rhabdomyolysis, AKI (KDIGO stage 3), patients who already received RRT prior to ICU admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of early (on admission) or late (5th day) ARC in critically ill adult patientsTimepoint: On admission and 5th day. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To correlate the CrCl measured using urine creatinine at 8-hour urine collection & serum creatinine with calculated CrCl using other methods: Modified Cockgroft Gault formula, 4- variable Modification of Diet in Renal Disease (MDRD-4) equation & Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). 2. Clinical outcomes in patients with ARC on admission (early) or late ARC (day 5) such as days of mechanical ventilation, requirement of vasopressor/inotrope, length of stay (LOS) in ICU & mortality. 3. Incidence of patients with ARC on admission developing acute kidney injury (AKI) with or without requirement of renal replacement therapy (RRT) during ICU stay, as defined by Kidney Disease: Improving Global Outcome (KDIGO) classification. 4. Factors affecting incidence of ARC. Timepoint: At day 1,day 5 & day of discharge | — |
Countries
India
Contacts
Postgraduate Institute of Medical Education and Research,Chandigarh