Comparison of dexamethasone and dexmedetomidine nebulization for reduction in incidence and severity of sore throat after laparoscopic gall bladder surgery in adult patients

Comparative evaluation of nebulized dexamethasone with nebulized dexmedetomidine for reduction in incidence of post-operative sore throat in patients undergoing laparoscopic cholecystectomy under general anesthesia with endotracheal intubation - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093168

Enrollment

132

Registered

2025-08-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: Dexmedetomidine: nebulized Dexmedetomidine 50mcg diluted to 5ml with normal saline Control Intervention1: Dexamethasone: 8mg nebulized Dexamethasone dilute to 5ml with normal saline

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 ASA 2 Scheduled for elective laparoscopic cholecystectomy surgery

Exclusion criteria

Exclusion criteria: ASA 3 ASA 4 history of allergy to study drugs anticipated difficult airway uncontrolled comorbid conditions

Design outcomes

Secondary

Measure	Time frame
incidence of hoarseness of voice, coughTimepoint: 2 hours, 6 hours, 12 hours, 24 hours after extubation	—

Primary

Measure	Time frame
incidence and severity of postoperative sore throatTimepoint: 2 hours, 6 hours, 12 hours, 24 hours after extubation	—

Countries

India

Contacts

Public ContactABHISHEK CHATTERJEE

TATA MAIN HOSPITAL

dona6991@rediffmail.com7541943869

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026