Health Condition 1: C678- Malignant neoplasm of overlappingsites of bladder Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: TURBT Group: Standard transurethral resection using electrocautery.
HolERBT Group: En-bloc resection using a holmium laser.
: Participants will be randomly assigned to either the cTURB
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: Tumor size less than or equal to 3cm. Number of tumors less than 3 in number No prior intravesical therapy.
Exclusion criteria
Exclusion criteria: Muscle-invasive bladder cancer. Tumors located in areas difficult to access endoscopically. Ureteral involvement Metastatic bladder tumour Patients with coagulopathies or on anticoagulant therapy that cannot be safely discontinued. Severe comorbidities contraindicating surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of detrusor muscle in the resected specimen, indicating the quality of resectionTimepoint: 14 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence-Free Survival (RFS): Defined as the time from the date of the initial resection to the first documented recurrence of bladder cancer, confirmed by follow-up cystoscopic evaluations.Timepoint: 3months,6months, and 12months | — |
Countries
India
Contacts
Public ContactSubeesh P
Government Medical College Kozhikode
Outcome results
None listed