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Comparing Nalbuphine and Fentanyl intraoperatively to reduce postoperative need and use of Morphine.

Comparison of Nalbuphine and Fentanyl in spine surgeries to determine postoperative requirement of Analgesia using PCA - Morphine. - Randomized Control Trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093138
Enrollment
60
Registered
2025-08-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Fentanyl: A single does of injection Fentanyl given at 2 micrograms per kg for perioperative analgesia. Control Intervention1: Nalbuphine: A single dose of injection Nalbuphine given at

Sponsors

SRM Medical college Hospital and research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for elective spine surgery requiring laryngoscopy and endotracheal intubation. Age 18-65. ASA - I & II. Surgery duration less than 120 minutes.

Exclusion criteria

Exclusion criteria: Allergy. Pregnancy or lactation.

Design outcomes

Primary

MeasureTime frame
To determine analgesic requirement of PCA ? Morphine postoperativelyTimepoint: To determine analgesic requirement of PCA ? Morphine postoperatively, every 2 hours for 24 hours—

Secondary

MeasureTime frame
To assess hemodynamic changes & side effects of Fentanyl. To assess hemodynamic changes & side effects of Nalbuphine.Timepoint: every 15 minutes intraoperatively from time of induction till the end of surgery—

Countries

India

Contacts

Public ContactPushparani Anand

SRM Medical college Hospital and research center

praneeth.koneru@gmail.com9177486629

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026