Comparative evaluation of efficacy, hemodynamic changes, and postoperative complications of 2% lidocaine using inferior alveolar nerve block and 4% articaine using intraosseous anaesthesia in mandibular primary molars of children aged 6 to 8 years: An in vivo, randomized, controlled study

Comparative evaluation of efficacy, hemodynamic changes, and postoperative complications of 2 percent lidocaine using inferior alveolar nerve block and 4 percent articaine using intraosseous anaesthesia in mandibular primary molars of children aged 6 to 8 years: An in vivo, randomized, controlled study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093134

Enrollment

Registered

2025-08-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Inferior alveolar nerve block: Injecting 2% lidocaine in primary mandibular molars that require pulp therapy duration of anesthesia pain during procedures and pstoperative complications

Eligibility

Inclusion criteria

Inclusion criteria: Aged 6-8 years Medically fit children Mentally capable of communication Having mandibular primary molar tooth that require pulp therapy Tooth without having any kind of history of infection (abscess) or swelling and no evidence of periapical pathosis or soft tissue infection/inflammation near the site of injection. Children, who are cooperative enough to undergo dental procedures and parental informed written consent provided. Tooth, which will give a baseline reading on pulp tester before administration of local anaesthetics.

Exclusion criteria

Exclusion criteria: Medically and mentally compromised children. History of significant behaviour management problems. Evidence of infection near the proposed injection site as this might affect the efficacy of local anaesthesia like periodontal (periodontal pockets or tooth mobility), radiological alterations (bone loss or periapical radio transparencies). Children who did not speak or understand local language. Children who are allergic to 4% articaine.

Design outcomes

Primary

Measure	Time frame
Intraosseous Anaesthesia using 4% articaine with needle guide system shows: Faster onset of action in mins Better pain control during procedures using WBFS, VAS and SEM scale Timepoint: Evaluation will be done at the baseline and one week	—

Secondary

Measure	Time frame
Intraosseous Anaesthesia using 4% articaine with needle guide system showed: Minimal hemodynamic changes like increase in heart rate Lower incidence of postoperative complications like soft tissue injuries within 24 hours Timepoint: Evaluation will be done at the baseline & one week	—

Countries

India

Contacts

Public ContactHinal Kanabar

Pacific Dental College And Hospital

pedodinesh2003@yahoo.co.in09265289652

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026