Study to Compare Infection Levels on Regular and curcumin-Coated Stitches Used in Gum Surgery

Comparative evaluation of anti-bacterial effect of silk suture coated with curcumin nano particles and uncoated silk suture in periodontal flap surgery: A Microbiological study. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/093103

Enrollment

Registered

2025-08-14

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Curcumin nanoparticle coated silk suture: The intervention agent is a non-absorbable silk surgical suture 3-0 coated with curcumin nanoparticles. Curcumin a natural polyphenolic compoun

Eligibility

Inclusion criteria

Inclusion criteria: Patients with age between 25 to 60 years Patients with Chronic Generalized Periodontitis Patients with at least 30 percent of the sites with pocket probing depth more than or equal to 5 mm after phase I therapy Patients willing to participate in the study with written informed consent

Exclusion criteria

Exclusion criteria: Patients who are pregnant or lactating mothers Patients who are immunocompromised patients Patients with any history of allergy to any material used in the study Patients who have undergone antibiotic therapy in past 3 months Patients with any systemic diseases

Design outcomes

Primary

Measure	Time frame
The total microbial count on curcumin nanoparticle coated suture sample and uncoated suture sample will be calculated after culturing on agar plate.Timepoint: The microbiological analysis will be done on the suture samples obtained from each study participant 7 days after the flap surgery	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Vidisha Naik

Bharati Vidyapeeth Deemed to be University Dental College and Hospital Pune

pramodw42@gmail.com9850846820

Outcome results