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Evaluating the effect of buprenorphine patch applied prior surgery for postoperative pain relief applied before surgery in patients with femur fracuture

Buprenorphine patch as a preemptive analgesia in fracture femur patients - A prospective randomized controlled study - Nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/093020
Enrollment
80
Registered
2025-08-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: group 1: Group-1 will receive buprenorphine patch of 10 mg 24 hours prior to surgery. Baseline VAS Score will be recorded, at the time of mobilisation,at positioning for subarachnoid bl

Sponsors

Om vasavi palam
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring fracture femur surgeries under subarachnoid blocks

Exclusion criteria

Exclusion criteria: 1- Patients who are not willing to participate 2- Patients with multiple fractures that would add to the discomfort and need of epidural 3- Obese patients 4- Severe liver or cardiorespiratory disease 5- Altered mental status 6- Patients on antidepressants 7- Patients with allergic history to opioids 8- Patients with chronic pain because of some other conditions or having arthritic pain. 9- Conditions requiring general anesthesia

Design outcomes

Primary

MeasureTime frame
To assess effectiveness of buprenorphine patch applied preoperatively 24 hours prior as perioperative analgesiaTimepoint: 4 hours, 8 hours, 12 hours and 24 hours after surgery

Secondary

MeasureTime frame
1- To assess analgesic requirements 2- To assess patient satisfaction 3- To assess development of any complications like respiratory depression, nausea, vomiting, shivering, pruritus and hemodynamic instability.Timepoint: With the above study we will be assessing the analgesic requirements or development of any complications during preoperative intraoperative or postoperative period.

Countries

India

Contacts

Public ContactSapna Nikhar

Nizams Institute of medical sciences, Hyderabad

sapnanikhar@gmail.com9030460262

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026