Health Condition 1: A419- Sepsis, unspecified organism
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
ESIC Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients with sepsis and SOFA score more than 2
Exclusion criteria
Exclusion criteria: 1 Patients and /or next of kin in ventilated patients or those unwilling to give consent for participation in the study 2 Patients with sample suspected of contamination during collection, processing or storage will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antibiotics therapy will be proposed on basis of PCR results will be compared with the empirical therapy already delivered to the patients Timepoint: At the time of admission only | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. number of de-esclation (defined as discontinuation of any companion drug and/or switch of the pivotal drug to a narrow spectrum antibiotics) of the antibiotics regimen based on PCR results. 2. Number of episodes in which PCR guided therapy will be effective on pathogens isolated at significant threshold on cultures. Timepoint: Modification of antimicrobials after receiving PCR report on day 1 & culture report from day 3-5 as soon as positive | — |
Countries
India
Contacts
Public ContactSumit Kumar
ESIC Medical College and Hospital
Outcome results
None listed