Health Condition 1: N183- Chronic kidney disease, stage 3 (moderate) Health Condition 2: N184- Chronic kidney disease, stage 4 (severe)
Conditions
Interventions
Intervention1: yoga: 12 week yoga intervention
Control Intervention1: none: not applicable
Sponsors
Dr Rima Dada
Eligibility
Inclusion criteria
Inclusion criteria: CKD stage 3 & 4 patients, Mentally and physically fit up to a level to understand and perform yogic asanas, Not enrolled in regular yoga practice
Exclusion criteria
Exclusion criteria: Exclusion criteria will be HIV, HCV HBsAg +ve patients, individuals with severe cardiovascular conditions active infection, respiratory conditions COPD, neurological disorder and cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 25% reduction in Proteinuria Timepoint: After 3 months of yoga intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Stable eGFR (estimated glomerular filtration rate) or increase in eGFRTimepoint: After 3 months of yoga intervention;Reduction in markers of inflammation and oxidative stress post yogaTimepoint: After 3 months of yoga intervention ;Markers of CKD metabolic bone disease and kidney injury will toward normalTimepoint: After 3 months of yoga intervention;Reduction in adipokine levels in bloodTimepoint: After 3 months of yoga intervention;Expression and methylation pattern of genes involved in CKD will come toward normalTimepoint: After 3 months of yoga intervention;Profibrotic miRNA in urinary exosomes should decreaseTimepoint: After 3 months of yoga intervention;Improvement in quality of lifeTimepoint: After 3 months of yoga intervention | — |
Countries
India
Contacts
Public ContactDr Rima Dada
AIIMS, New Delhi
Outcome results
None listed