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Effect of use of PRF apical plug with conventional root canal treatment on periradicular tissue healing

Comparative evaluation of the effect of conventional root canal treatment with PRF apical plug versus without on periradicular tissues healing: A randomized clinical trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092971
Enrollment
100
Registered
2025-08-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K042- Pulp degeneration

Interventions

Intervention1: Platelet Rich Fibrin with root canal treatment: Platelet Rich Fibrin will be placed as apical plug in cases with periradicular pathology undergoing root canal treatment Control Interven

Sponsors

All India Institute of Medical Sciences Bathinda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients with periradicular pathology and indicated for root canal treatment. Permanent mandibular molars patients willing for written informed consent and follow up visits

Exclusion criteria

Exclusion criteria: Patients suffering from systemic diseases like diabetes mellitus, osteoporosis Patients with poor periodontal health and tooth mobility Patients with mandibular molars used as an abutment

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of Platelet rich fibrin apical plug on healing of periradicular tissues in cases of periradicular pathologyTimepoint: To evaluate the effect of Platelet rich fibrin apical plug on healing of periradicular tissues in cases of periradicular pathology at 1 month, 3 months and 6 months—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr Aakash Gupta

All India Institute of Medical Sciences Bathinda

guptaaakash95@gmail.com09877939523

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026